In this paper, we propose a new approach to learned optimization. As common in the literature, we represent the computation of the update step of the optimizer with a neural network. The parameters of the optimizer are then learned on a set of training optimization tasks, in order to perform minimisation efficiently. Our main innovation is to propose a new neural network architecture for the learned optimizer inspired by the classic BFGS algorithm. As in BFGS, we estimate a preconditioning matrix as a sum of rank-one updates but use a transformer-based neural network to predict these updates jointly with the step length and direction. In contrast to several recent learned optimization approaches, our formulation allows for conditioning across different dimensions of the parameter space of the target problem while remaining applicable to optimization tasks of variable dimensionality without retraining. We demonstrate the advantages of our approach on a benchmark composed of objective functions traditionally used for evaluation of optimization algorithms, as well as on the real world-task of physics-based reconstruction of articulated 3D human motion.

我们研究了一个体现的设置中的终身视觉感知，在那里我们开发了新的模型，并比较了在建筑物中导航的各种代理，偶尔会要求注释，又用于改进他们的视觉感知能力。代理的目的是在结合探索和主动视觉学习的过程结束时识别整个建筑物中的对象和其他语义类。当我们在终身学习背景下研究这项任务时，代理商应该使用早期访问环境中获得的知识，以便在连续访问建筑物中指导他们的勘探和积极学习策略。我们使用语义分割性能作为一般性视觉感知的代理，并研究了几种探索和注释方法的新任务，从使用启发式主动学习的前沿勘探基线到一个完全学习的方法。对于后者，我们介绍了一个基于深度的加强学习（RL）的代理，共同学习了导航和主动学习。一个点目标导航制定，与提供目标的全球计划者耦合，被集成到RL模型中，以便为新颖的场景系统探索提供进一步的激励措施。通过在TAKEPORT3D DataSet上进行广泛的实验，我们展示了拟议的代理商如何利用先前探索的场景的知识，例如，探索新的，例如，通过更少的粒度勘探和较少频繁的注释请求。结果还表明，基于学习的代理能够比启发式替代品更有效地使用其先前的视觉知识。

There are multiple scales of abstraction from which we can describe the same image, depending on whether we are focusing on fine-grained details or a more global attribute of the image. In brain mapping, learning to automatically parse images to build representations of both small-scale features (e.g., the presence of cells or blood vessels) and global properties of an image (e.g., which brain region the image comes from) is a crucial and open challenge. However, most existing datasets and benchmarks for neuroanatomy consider only a single downstream task at a time. To bridge this gap, we introduce a new dataset, annotations, and multiple downstream tasks that provide diverse ways to readout information about brain structure and architecture from the same image. Our multi-task neuroimaging benchmark (MTNeuro) is built on volumetric, micrometer-resolution X-ray microtomography images spanning a large thalamocortical section of mouse brain, encompassing multiple cortical and subcortical regions. We generated a number of different prediction challenges and evaluated several supervised and self-supervised models for brain-region prediction and pixel-level semantic segmentation of microstructures. Our experiments not only highlight the rich heterogeneity of this dataset, but also provide insights into how self-supervised approaches can be used to learn representations that capture multiple attributes of a single image and perform well on a variety of downstream tasks. Datasets, code, and pre-trained baseline models are provided at: https://mtneuro.github.io/ .

Logic Mill is a scalable and openly accessible software system that identifies semantically similar documents within either one domain-specific corpus or multi-domain corpora. It uses advanced Natural Language Processing (NLP) techniques to generate numerical representations of documents. Currently it leverages a large pre-trained language model to generate these document representations. The system focuses on scientific publications and patent documents and contains more than 200 million documents. It is easily accessible via a simple Application Programming Interface (API) or via a web interface. Moreover, it is continuously being updated and can be extended to text corpora from other domains. We see this system as a general-purpose tool for future research applications in the social sciences and other domains.

In this paper we take the first steps in studying a new approach to synthesis of efficient communication schemes in multi-agent systems, trained via reinforcement learning. We combine symbolic methods with machine learning, in what is referred to as a neuro-symbolic system. The agents are not restricted to only use initial primitives: reinforcement learning is interleaved with steps to extend the current language with novel higher-level concepts, allowing generalisation and more informative communication via shorter messages. We demonstrate that this approach allow agents to converge more quickly on a small collaborative construction task.

High content imaging assays can capture rich phenotypic response data for large sets of compound treatments, aiding in the characterization and discovery of novel drugs. However, extracting representative features from high content images that can capture subtle nuances in phenotypes remains challenging. The lack of high-quality labels makes it difficult to achieve satisfactory results with supervised deep learning. Self-Supervised learning methods, which learn from automatically generated labels has shown great success on natural images, offer an attractive alternative also to microscopy images. However, we find that self-supervised learning techniques underperform on high content imaging assays. One challenge is the undesirable domain shifts present in the data known as batch effects, which may be caused by biological noise or uncontrolled experimental conditions. To this end, we introduce Cross-Domain Consistency Learning (CDCL), a novel approach that is able to learn in the presence of batch effects. CDCL enforces the learning of biological similarities while disregarding undesirable batch-specific signals, which leads to more useful and versatile representations. These features are organised according to their morphological changes and are more useful for downstream tasks - such as distinguishing treatments and mode of action.

Objective: Imbalances of the electrolyte concentration levels in the body can lead to catastrophic consequences, but accurate and accessible measurements could improve patient outcomes. While blood tests provide accurate measurements, they are invasive and the laboratory analysis can be slow or inaccessible. In contrast, an electrocardiogram (ECG) is a widely adopted tool which is quick and simple to acquire. However, the problem of estimating continuous electrolyte concentrations directly from ECGs is not well-studied. We therefore investigate if regression methods can be used for accurate ECG-based prediction of electrolyte concentrations. Methods: We explore the use of deep neural networks (DNNs) for this task. We analyze the regression performance across four electrolytes, utilizing a novel dataset containing over 290000 ECGs. For improved understanding, we also study the full spectrum from continuous predictions to binary classification of extreme concentration levels. To enhance clinical usefulness, we finally extend to a probabilistic regression approach and evaluate different uncertainty estimates. Results: We find that the performance varies significantly between different electrolytes, which is clinically justified in the interplay of electrolytes and their manifestation in the ECG. We also compare the regression accuracy with that of traditional machine learning models, demonstrating superior performance of DNNs. Conclusion: Discretization can lead to good classification performance, but does not help solve the original problem of predicting continuous concentration levels. While probabilistic regression demonstrates potential practical usefulness, the uncertainty estimates are not particularly well-calibrated. Significance: Our study is a first step towards accurate and reliable ECG-based prediction of electrolyte concentration levels.

Inductive reasoning is a core component of human intelligence. In the past research of inductive reasoning within computer science, logic language is used as representations of knowledge (facts and rules, more specifically). However, logic language can cause systematic problems for inductive reasoning such as disability of handling raw input such as natural language, sensitiveness to mislabeled data, and incapacity to handle ambiguous input. To this end, we propose a new task, which is to induce natural language rules from natural language facts, and create a dataset termed DEER containing 1.2k rule-fact pairs for the task, where rules and facts are written in natural language. New automatic metrics are also proposed and analysed for the evaluation of this task. With DEER, we investigate a modern approach for inductive reasoning where we use natural language as representation for knowledge instead of logic language and use pretrained language models as ''reasoners''. Moreover, we provide the first and comprehensive analysis of how well pretrained language models can induce natural language rules from natural language facts. We also propose a new framework drawing insights from philosophy literature for this task, which we show in the experiment section that surpasses baselines in both automatic and human evaluations.

Industry 4.0 aims to optimize the manufacturing environment by leveraging new technological advances, such as new sensing capabilities and artificial intelligence. The DRAEM technique has shown state-of-the-art performance for unsupervised classification. The ability to create anomaly maps highlighting areas where defects probably lie can be leveraged to provide cues to supervised classification models and enhance their performance. Our research shows that the best performance is achieved when training a defect detection model by providing an image and the corresponding anomaly map as input. Furthermore, such a setting provides consistent performance when framing the defect detection as a binary or multiclass classification problem and is not affected by class balancing policies. We performed the experiments on three datasets with real-world data provided by Philips Consumer Lifestyle BV.

Quality control is a crucial activity performed by manufacturing companies to ensure their products conform to the requirements and specifications. The introduction of artificial intelligence models enables to automate the visual quality inspection, speeding up the inspection process and ensuring all products are evaluated under the same criteria. In this research, we compare supervised and unsupervised defect detection techniques and explore data augmentation techniques to mitigate the data imbalance in the context of automated visual inspection. Furthermore, we use Generative Adversarial Networks for data augmentation to enhance the classifiers' discriminative performance. Our results show that state-of-the-art unsupervised defect detection does not match the performance of supervised models but can be used to reduce the labeling workload by more than 50%. Furthermore, the best classification performance was achieved considering GAN-based data generation with AUC ROC scores equal to or higher than 0,9898, even when increasing the dataset imbalance by leaving only 25\% of the images denoting defective products. We performed the research with real-world data provided by Philips Consumer Lifestyle BV.